Professor Nick Morrell
Professor Nick Morrell is Director of Studies in Clinical Medicine. He is the British Heart Foundation Professor of Cardiopulmonary Medicine, in the Department of Medicine at the University of Cambridge School of Clinical Medicine and the Research Director of the National Pulmonary Hypertension service at Papworth Hospital. He runs a research laboratory in the Department of Medicine at Addenbrooke's Hospital studying the genetics and molecular basis of rare but important cardiovascular diseases, particularly pulmonary arterial hypertension, and is developing new treatments for these conditions.
- Richard C. Trembath, Jennifer R. Thomson, Rajiv D. Machado, Neil V. Morgan, Carl Atkinson, Ingrid Winship, Gerald Simonneau, Nazzareno Galie, James E. Loyd, Marc Humbert, William C. Nichols, Jonathan Berg, Alessandra Manes, Julie McGaughran, Michael Pauciulo, Lisa Wheeler, and Nicholas W. Morrell. Clinical and Molecular Genetic Features of Pulmonary Hypertension in Patients with Hereditary Hemorrhagic Telangiectasia. N Engl J Med 2001; 345:325-334
- Carl Atkinson, Susan Stewart, Paul D. Upton, Rajiv Machado, Jennifer R. Thomson, Richard C. Trembath, Nicholas W. Morrell. Primary Pulmonary Hypertension Is Associated With Reduced Pulmonary Vascular Expression of Type II Bone Morphogenetic Protein Receptor. Circulation 2002;105: 1672-1678
- Nicholas W. Morrell, Serge Adnot, Stephen L. Archer, Jocelyn Dupuis, Peter Lloyd Jones, Margaret R. MacLean, Ivan F. McMurtry, Kurt R. Stenmark, Patricia A. Thistlethwaite, Norbert Weissmann, Jason X.-J. Yuan, E. Kenneth Weir. Cellular and Molecular Basis of Pulmonary Arterial Hypertension. J Am Coll Cardiol. 2009;54(1s1):S20-S31
- Nicholas W. Morrell, Xudong Yang, Paul D. Upton, Karen B. Jourdan, Neal Morgan, Karen K. Sheares, Richard C. Trembath. Altered Growth Responses of Pulmonary Artery Smooth Muscle Cells From Patients With Primary Pulmonary Hypertension to Transforming Growth Factor-?1 and Bone Morphogenetic Proteins.Circulation 2001; 104: 790-795
- Xudong Yang, Lu Long, Mark Southwood, Nung Rudarakanchana, Paul D. Upton, Trina K. Jeffery, Carl Atkinson, Hailan Chen, Richard C. Trembath, Nicholas W. Morrell. Dysfunctional Smad Signaling Contributes to Abnormal Smooth Muscle Cell Proliferation in Familial Pulmonary Arterial Hypertension. Circulation Research 2005; 96: 1053-1063.