Dr John Xuereb

Emeritus Fellow
Neurodegenerative diseases
Senior Proctor 2018-19; Deputy Senior Proctor 2019-20

Early NHS career: physician in Manchester Teaching Hospitals and neurologist in Newcastle upon Tyne.
University of Cambridge (1993 -2020): Fellow and Director of Studies in Pathology at St Catharine's College.
Cambridge University Hospitals NHS Foundation Trust (1991-2015): Honorary Consultant Neuropathologist.    
Royal College of Pathologists: Chair, Panel of Examiners for Fellowship (FRCPath in Neuropathology) 2007-2015; Chair, RCPath Specialty Advisory Committee for Neuropathology 2011-15.
European Confederation of Neuropathological Societies (Euro-CNS): Chair, Board of Examiners for the European Fellowship in Neuropathology 2007-2015.
Clinical Pathology Accreditation (UK): Member of panel of assessors 2004-2015.
Dean of St Catharine's College 2001-2011 and 2015-2020.

Xuereb JH, Perry RH, Candy JM, Perry EK, Marshall E, Bonham JR. Nerve cell loss in the thalamus in Alzheimer's disease and Parkinson's disease. Brain. 1991 Jun;114 ( Pt 3):1363-79.

Xuereb JH, Candy JM, Perry EK, Perry RH, Marshall E, Bonham JR. Distribution of neurofibrillary tangle formation and [3H]-D-aspartate receptor binding in the thalamus in the normal elderly brain, in Alzheimer's disease and in Parkinson's disease. Neuropathol Appl Neurobiol. 1990 Dec;16(6):477-88.

Xuereb JH, Perry EK, Candy JM, Bonham JR, Perry RH, Marshall E. Parameters of
cholinergic neurotransmission in the thalamus in Parkinson's disease and Alzheimer's disease. J Neurol Sci. 1990 Nov;99(2-3):185-97.

Xuereb JH, MacMillan JC, Snell R, Davies P, Harper PS. Neuropathological diagnosis and CAG repeat expansion in Huntington's disease. J Neurol Neurosurg Psychiatry. 1996 Jan;60(1):78-81

Gertz HJ, Xuereb J, Huppert F, Brayne C, McGee MA, Paykel E, Harrington C,
Mukaetova-Ladinska E, Arendt T, Wischik CM. Examination of the validity of the hierarchical model of neuropathological staging in normal aging and Alzheimer's disease. Acta Neuropathol. 1998 Feb;95(2):154-8

Xuereb JH, Brayne C, Dufouil C, Gertz H, Wischik C, Harrington C,
Mukaetova-Ladinska E, McGee MA, O'Sullivan A, O'Connor D, Paykel ES, Huppert FA.
Neuropathological findings in the very old. Results from the first 101 brains of a population-based longitudinal study of dementing disorders. Ann N Y Acad Sci. 2000 Apr;903:490-6.

Galton CJ, Patterson K, Xuereb JH, Hodges JR. Atypical and typical presentations of Alzheimer's disease: a clinical, neuropsychological, neuroimaging and pathological study of 13 cases. Brain. 2000 Mar;123 Pt 3:484-98.

Corti C, Sala CF, Yang F, Corsi M, Xuereb JH, Ferraguti F. Genomic organization of the human metabotropic glutamate receptor subtype 3. J Neurogenet. 2000 Dec;14(4):207-25, 271.

Corti C, Xuereb JH, Corsi M, Ferraguti F. Identification and characterization of the promoter region of the GRM3 gene. Biochem Biophys Res Commun. 2001 Aug 17;286(2):381-7.

Ferraguti F, Corti C, Valerio E, Mion S, Xuereb J. Activated astrocytes in areas of kainate-induced neuronal injury upregulate the expression of the metabotropic glutamate receptors 2/3 and 5. Exp Brain Res. 2001 Mar;137(1):1-11.

Graham A, Davies R, Xuereb J, Halliday G, Kril J, Creasey H, Graham K, Hodges
J. Pathologically proven frontotemporal dementia presenting with severe amnesia.
Brain. 2005 Mar;128(Pt 3):597-605

Davies RR, Graham KS, Xuereb JH, Williams GB, Hodges JR. The human perirhinal cortex and semantic memory. Eur J Neurosci. 2004 Nov;20(9):2441-6.

Hodges JR, Davies RR, Xuereb JH, Casey B, Broe M, Bak TH, Kril JJ, Halliday GM. Clinicopathological correlates in frontotemporal dementia. Ann Neurol. 2004 Sep;56(3):399-406.

Davies RR, Hodges JR, Kril JJ, Patterson K, Halliday GM, Xuereb JH. The pathological basis of semantic dementia. Brain. 2005 Sep;128(Pt 9):1984-95

Knibb JA, Xuereb JH, Patterson K, Hodges JR. Clinical and pathological characterization of progressive aphasia. Ann Neurol. 2006 Jan;59(1):156-65.

Davies RR, Halliday GM, Xuereb JH, Kril JJ, Hodges JR. The neural basis of semantic memory: evidence from semantic dementia. Neurobiol Aging. 2009 Dec;30(12):2043-52.

Del Bigio MR, Hainfellner JA, McLean CA, Powell SZ, Sikorska B, Takahashi H, Weis J, Xuereb JH. Neuropathology training worldwide-evolution and comparisons.
Brain Pathol. 2014 Apr;24(3):285-98