Michael Nicholson is Professor of Transplant Surgery and Head of the Division of Academic General & Transplant Surgery at the University of Cambridge. He is also an Honorary Consultant Surgeon at Addenbrooke’s Hospital.
He qualified from Nottingham University and trained in general and transplant surgery in Nottingham, Bristol, Leicester and Oxford. He is the lead for live donor kidney transplantation in Cambridge and has performed 700 laparoscopic live donor nephrectomies and 1100 kidney transplants.
He is the Director of the NIHR Blood and Transplant Research Unit in Organ Donation and Transplantation (odt.btru.nihr.ac.uk). His research group focus on developing renal normothermic machine perfusion with the aim of assessing marginal kidneys and delivering pre-transplant allograft therapies. He has published more than 360 papers, supervised 33 successfully awarded doctorates and raised more than £15M in external grant funding.
DiRito JR, Hosgood SA, Reschke M, Albert C, Bracaglia LG, Ferdinand JR, Stewart BJ, Edwards CM, Vaish AG, Thiru S, Mulligan DC, Haakinson DJ, Clatworthy MR, Saltzman WM, Pober JS, Nicholson ML, Tietjen GT.
Lysis of cold-storage-induced microvascular obstructions for ex vivo revitalisation of marginal human kidneys.
Am J Transplant 2020; Jul 5: online ahead of print PMID 32627324
Thompson ER, Bates L, Ibrahim KI, Avinash S, Stenberg B, McNeill A, Figueiredo R, Girdlestone T, Wilkins GC, Wang L, Tingle SJ, Scott WE, Lamos H, Mellor AL, Roobrouck VD, Ting AE, Hosgood SA, Nicholson ML, Fisher AJ, Ali S, Sheerin NS, Wilson CH.
Novel delivery of cellular therapy to reduce ischaemia reperfusion injury in kidney transplantation.
Am J Transplant 2020; Jun 7: online ahead of print PMID 32506663
Nicholson ML, Yong C, Trotter PB, Grant L, Hosgood SA.
Risk factors for transplant renal artery stenosis after live donor transplantation.
Brit J Surg 2019;106:199-205.
Hosgood SA, Thompson E, Moore TA, Wilson CH, Nicholson ML.
Normothermic machine perfusion for the assessment and transplantation of declined human kidneys from donation after circulatory death donors.
Brit J Surg 2018;105:388-394.
Tietjen GT, Hosgood SA, Kirkiles-Smith NC, Cui J, Piotrowski-Daspit AS, Deep D, Song E, DiRito J, Al-Lamki R, Bradley A, Saeb-Parsy K, Bradley JR, Nicholson ML, Saltzman WM, Pober JS.
Antibody-targeting can increase nanoparticle delivery to endothelial cells during ex vivo normothermic machine perfusion of human kidney.
Science Translational Medicine 2017;29:418.
Hosgood SA, Saeb-Parsy K, Hamed MO, Nicholson ML.
Successful transplantation of human kidneys deemed untransplantable but resuscitated by ex-vivo normothermic machine perfusion.
Am J Transplant 2016:16:3282-85.
Hosgood SA, Barlow AD, Hunter JP, Nicholson ML.
Ex vivo normothermic perfusion for quality assessment of marginal donor kidneys
Br J Surg 2015;102:1433-40.
Nicholson ML, Pattenden CJ, Barlow AD, Hunter JP, Lee G, Hosgood SA.
A double blind randomized clinical trial of remote ischemic conditioning in live donor renal transplantation.
Nicholson ML, Hosgood SA.
Renal Transplantation after normothermic perfusion: the first clinical study.
Am J Transplant 2013;13:1246-52
Hosgood SA, Nicholson ML. Age and cold storage in kidneys from
Nicholson ML, Kaushik M, Lewis GR, Brook NR, Bagul A, Kay MD, Harper SJ, Elwell R, Veitch PS.
Randomized clinical trial of laparoscopic versus open donor nephrectomy.
Br J Surg 2010;97:21-8.
Brook NR, Nicholson ML. Non-directed live kidney donation.
Nicholson ML, Metcalfe MS, White SA, Doughman TM, Horsburgh T, Feehally J, Carr SJ, Veitch PS. Comparison of the results of renal transplantation from non-heart beating, conventional cadaveric and living donors.
Kidney International 2000; 58: 2585-2591.